Analyzing the shift from traditional herbal remedies to pharmaceutical-grade venotonics.
Daflon, primarily composed of a Micronized Purified Flavonoid Fraction (MPFF), typically contains 90% Diosmin and 10% Hesperidin. The global trend is shifting toward ultra-micronization to enhance bioavailability. Modern companies are investing in air-jet milling to achieve particle sizes under 2 microns, significantly improving intestinal absorption compared to non-micronized alternatives.
Chronic Venous Insufficiency (CVI) and hemorrhoidal disease are increasing due to sedentary lifestyles and aging global demographics. This has catalyzed a massive demand for CE-certified Diosmin, particularly in the EU and emerging markets in Asia-Pacific, where regulatory scrutiny on active pharmaceutical ingredients (APIs) is tightening.
Leading manufacturers like Chenlv Herb are focusing on the circular economy, sourcing raw materials from immature Citrus aurantium fruits. Ethical supply chains and "green extraction" methods using eco-friendly solvents are no longer optional but a prerequisite for global pharmaceutical procurement.
Established in 2012, Chenlv Herb is a high-tech enterprise specializing in the R&D, production, and sales of botanical extracts and natural pharmaceutical ingredients. We provide high-purity, highly active, and premium-quality natural raw materials for pharmaceuticals, health supplements, food, and cosmetics industries.
Years Expertise
Factory Area
Global Clients
The journey begins with Hesperidin extraction from citrus peels, followed by a sophisticated dehydrogenation process to synthesize Diosmin. Our technical route ensures a purity of >95%, meeting USP and EP standards.
Using proprietary chromatography, we remove impurities that cause gastrointestinal side effects. Our "Super-Fine" micronization process increases the surface area of the particles by 20x, ensuring rapid therapeutic onset.
Our products undergo rigorous testing including HPLC, GC-MS, and ICP-MS to ensure zero heavy metal contamination and solvent residue compliance with CE and FDA requirements.
How we support global pharmaceutical giants and distributors.
We provide stable supply chain solutions for wholesale buyers, ensuring price hedging against raw citrus market fluctuations. Our capacity allows for multi-ton monthly shipments of pharmaceutical-grade Diosmin.
Beyond raw powder, we offer granulated Diosmin/Hesperidin mixtures (9:1) ready for tableting or encapsulation, significantly reducing manufacturing lead times for our clients.
We assist in local regulatory filings, providing full dossier support (DMF, CEP) to ensure your final product gains CE marking and local health authority approval swiftly.
Choose Chenlv Herb for products that deliver beyond expectations
Creative designs and technical formulations that elevate your brand.
Eco-friendly packaging and streamlined production aligned with today’s values.
End-to-end cosmetic and pharmaceutical packaging solutions.
Fast turnaround and dedicated support to meet your global timelines.
Certified by ISO9001, ISO22000, HALAL, KOSHER, and FDA.
Years of expertise ensuring precision in natural ingredient extraction.
Natural raw materials for modern supplements focused on vascular health.
Active pharmaceutical ingredients (APIs) for chronic venous disease treatments.
Plant extracts used for soothing and micro-circulation enhancing skincare.
Natural additives to enhance production performance and animal immunity.
How we transform your requirements into high-quality products.
Requirements communication.
Requirement-based proposal.
Signing and detail finalization.
Demand-based customization.
Factory scheduling & output.
Testing and CoA issuance.
Global delivery to your door.
Expert insights into Diosmin and Daflon manufacturing.
We are integrating AI algorithms to predict the optimal harvest time for Citrus aurantium based on weather patterns, maximizing the concentration of natural hesperidin before extraction even begins.
Beyond micronization, research is moving toward nano-liposomal delivery systems for Diosmin, which could potentially reduce the required dosage while maintaining the same therapeutic effect, minimizing side effects.
Blockchain-based traceability from "Seed to Supplement" is our goal, allowing global buyers to scan a QR code and see the entire compliance history and carbon footprint of their Diosmin shipment.
Chenlv Herb
