Discover our highly standardized, certified plant extracts and pharmaceutical-grade ingredients available for bulk wholesale and custom formulation.
Overcoming bioavailability barriers to enhance the efficacy of Trans-Resveratrol in endothelial wellness and microvascular applications.
Trans-resveratrol is known for poor aqueous solubility (log P = 3.1) and rapid metabolism in the human gut. Our R&D team uses advanced liposomal encapsulation and lipid-based self-microemulsifying drug delivery systems (SMEDDS). Encapsulating resveratrol in phospholipid bilayers improves its stability against gastrointestinal enzymes and increases absorption by up to 400% compared to standard powders.
Resveratrol is a potent activator of sirtuin-1 (SIRT1), a key regulator of mitochondrial biogenesis and longevity pathways. Our ODM formulations combine trans-resveratrol with co-factors like quercetin and nicotinamide mononucleotide (NMN). This combination works synergistically: quercetin inhibits catechol-O-methyltransferase (COMT), slowing down resveratrol degradation, while NMN supports NAD+ availability to maximize overall cellular benefits.
For applications targeted at endothelial performance, vascular elasticity, and nitric oxide (NO) generation, resveratrol works as an organic vasodilator. By stimulating endothelial nitric oxide synthase (eNOS) transcription and inhibiting reactive oxygen species (ROS), it helps maintain vessel health and microcirculation, making it a valuable ingredient for men's wellness formulations.
Operating from Chengdu Chenlv Herb's 9,514㎡ high-tech production base, we combine automated extraction lines with green chemistry practices.
Located in Sichuan province, Chengdu Chenlv Herb Co., Ltd. has established a reliable supply chain by using local agricultural resources. We source premium raw materials, such as Polygonum cuspidatum (Giant Knotweed), ensuring a steady pipeline of starting material. This geographical advantage helps cushion against international raw material price volatility.
Our extraction facility utilizes supercritical CO2 fluid extraction and countercurrent column chromatography. These methods minimize organic solvent use, maximize trans-resveratrol yields, and prevent thermal degradation of active ingredients. Our automated process monitors temperature, pressure, and flow rates in real time, delivering consistent batch-to-batch quality.
Why leading global nutraceutical brands choose Chengdu Chenlv Herb as their primary raw materials partner.
Creative designs and bespoke formulation solutions that elevate your brand and improve product positioning.
Eco-friendly packaging and optimized manufacturing processes aligned with modern sustainability standards.
End-to-end cosmetic and nutraceutical packaging solutions built to minimize carbon footprint.
Fast response and production turnaround times designed to help you meet your target market launches.
A dedicated quality control team supporting you through audit compliance and chemical validation.
Years of industry expertise ensuring chemical precision and regulatory compliance in active botanicals.
Our 7-step process ensures clear communication and quality control from initial design to final dispatch.
01
Initial consult to define target specifications and concentration metrics.
02
Comprehensive cost breakdown, including logistics terms and lead times.
03
Signing agreements, IP protection clauses, and setting parameters.
04
Pilot extraction run to create laboratory samples for evaluation.
05
Scaling production using our GMP-compliant extraction lines.
06
In-house HPLC, heavy metal screening, and COA generation.
07
Secure packaging and shipping under temperature-controlled conditions.
Our botanical extracts serve pharmaceutical, cosmetic, and nutritional formulation industries worldwide.
Natural and standard botanical components designed for food and nutritional supplement products.
Active biological compounds prepared to meet pharmaceutical purity and testing standards.
Stable, mild plant extracts formulated for anti-aging and skin protective skincare applications.
Natural feed additives that support growth performance and gut health in animal husbandry.
Our manufacturing facility maintains key industry certifications, including ISO9001, ISO22000, HALAL, KOSHER, and FDA compliance.
Highly requested botanical raw materials for functional supplements and therapeutic formulations.
Selling health ingredients globally requires adhering to strict regional regulatory policies. Our quality control system ensures that our botanical extracts meet requirements set by agencies like the United States FDA, the European Food Safety Authority (EFSA), and China's National Medical Products Administration (NMPA).
For active resveratrol supplements, verifying the absence of contaminants is a critical part of our testing protocol. Every production run undergoes testing for polycyclic aromatic hydrocarbons (PAHs), heavy metals (such as lead, arsenic, and cadmium), and pesticide residues (via GC-MS/MS and LC-MS/MS). This thorough analysis helps our clients pass regulatory audits during their importation processes.
We also conduct real-time and accelerated stability studies. This data helps formulators determine the correct dosage for their products, ensuring active ingredients remain viable throughout the shelf life under different storage conditions (Zone II and Zone IVB climates).
Our facility utilizes high-performance liquid chromatography (HPLC) to confirm trans-isomer purity. This testing ensures that our active compounds deliver the desired chemical profile and physical consistency across every manufacturing batch.
Common questions regarding chemistry, extraction technology, and compliance verification for active raw materials.
Trans-resveratrol is the biologically active isomer associated with the activation of longevity pathways (SIRT1) and antioxidant benefits. Cis-resveratrol is less stable and typically shows lower biological activity. We test our batches to confirm they contain high concentrations of the trans-isomer.
We use solid dispersion and microencapsulation technologies to improve solubility. By dispersing the target compound within an organic carrier matrix, we increase the surface area available to water, which helps support dissolution and absorption.
Yes, Chengdu Chenlv Herb's manufacturing facility is registered with the FDA. We follow current Good Manufacturing Practices (cGMP) and generate full documentation, including Certificates of Analysis (COAs) and heavy metal profiles for all production runs.
Standard pilot samples are generally produced within 10 to 15 days. Commercial volume runs typically require 3 to 5 weeks, depending on formulation complexity, raw material sourcing, and specialized packaging needs.
Insights, events, and reports from the forefront of global botanical extraction technology.
A review of recent pricing shifts for Citrus aurantium raw materials during the late harvest season, exploring supply-demand dynamics and cost implications for manufacturers.
Chengdu Chenlv Herb invites industry partners to connect at CPHI China 2025 to discuss extraction methods, purity standards, and collaborative development opportunities.
We are attending API China in Guangzhou to showcase our latest high-purity natural active compounds and customization services for the supplement market.
Select premium specialty compounds and standardized herbal derivatives prepared for commercial packaging.
Chenlv Herb
